The 10th annual International Space Station Research and Development Conference (ISSRDC) took place virtually August 3-5, 2021, and was hosted by the Center for the Advancement of Science in Space (CASIS), manager of the International Space Station (ISS) National Laboratory; NASA; and the American Astronautical Society.

The theme for our 2021 conference was “Challenge. Partnership. Transformation.” The past couple of years have been filled with challenges that have required us to come together and transform how we think and work. Through partnership, we can achieve the transformation needed to address the many challenges we face today—here on Earth, in driving a robust economy in low Earth orbit, and as we advance our exploration goals to the Moon and beyond.